required for transition of stimulus - induced sharp wave - 1 ripple complexes into recurrent epileptiform discharges 2 in rat hippocampal slices 3
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چکیده
Partial disinhibition is required for transition of stimulus-induced sharp wave1 ripple complexes into recurrent epileptiform discharges 2 in rat hippocampal slices 3 Agustin Liotta#, Gürsel Çalışkan#, Rizwan ul Haq, Jan O. Hollnagel , Anton 4 Rösler, Uwe Heinemann 2 and Christoph J. Behrens 5 6 Institute of Neurophysiology, Institute for Physiology and 7 NeuroCure Research Center, Charité Universitätsmedizin Berlin, Charitéplatz 1, 8 10117 Berlin, Germany 9 # both authors contributed equally to the work 10 Running head: Partially reduced inhibition and sharp wave-ripples 11 12 Corresponding author: 13 Dr. Christoph J. Behrens 14 Institute for Neurophysiology, Johannes MüllerCenter for Physiology 15 Charité Universitätsmedizin Berlin, 16 Oudenarder Strasse 16, 13347 Berlin, Germany 17 E-mail: [email protected] 18 Tel: #49 30 450 52 81 49 19 Fax: #49 30 450 52 89 62 20 21 Running title: Sharp wave ripples and recurrent epileptiform discharges 22 23
منابع مشابه
Partial disinhibition is required for transition of stimulus-induced sharp wave-ripple complexes into recurrent epileptiform discharges in rat hippocampal slices.
Sharp wave-ripple complexes (SPW-Rs) in the intact rodent hippocampus are characterized by slow field potential transients superimposed by close to 200-Hz ripple oscillations. Similar events have been recorded in hippocampal slices where SPW-Rs occur spontaneously or can be induced by repeated application of high-frequency stimulation, a standard protocol for induction of long-lasting long-term...
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